Stop overpaying for under-results.
The purpose of Literature Lab is to give scientists clear, actionable answers from the analysis of their laboratory data, and in the process give a nudge to the creative and learning processes. From the outset of our research and development on Literature Lab we have targeted simplicity, economy and assuring confidence in the results of every analysis on the data that scientists work so hard to gather.
The biomedical literature record within PubMed is a rich source of associative information but it is too vast to permit comprehensive manual review. Since 1990 there are >27 million new publications. One or more human genes are mentioned in more than half of them, 15.5 million mention one or more pathways, 4 million discuss neoplastic disease, 2.5 million discuss CVD, a few hundred million drug references are buried, and so on. And modern high content genomic technologies are producing data at rates that outpace meaningful interpretation by legacy analysis platforms and conventional bioinformatics analysis.
We invite you to request Literature Lab BASIC reports of biology related to diseases and genes of interest. We can also provide you with a sample Literature Lab PLUS analysis of a laboratory dataset.
The Literature Lab™ suite of biomedical literature mining applications
.Literature Lab™ PLUS
Gives biological meaning to transcriptomic datasets, gene signatures, or putative gene panels, giving a thorough assessment of the biology in 25 domains of study, including pathways, diseases (4,300 diseases identified in the NCBI MeSH diseases ontology, as well as 4600 rare diseases), cell biology, metabolites, pathological conditions, inhibitors, chemicals & drugs, cancer drugs, immunology, physiology, metabolism, etc.. With Literature Lab™ PLUS you are freed from analyses based on a priori determinations, fixed databases of gene lists, or algorithms that you may not even understand.
At the core of the Literature Lab™ database is the Acumenta Biotech Gene Thesaurus™, a repository of gene, protein and pathway nomenclature gathered from the major genomic databases, and human-curated to produce searches combining high precision and high recall. The Gene Thesaurus™ is unique because it is constantly updated on the Literature™ Lab platform, and human curation resolves ambiguous terminology, alias redundancy and generic terms.
More about the Literature Lab™ PLUS functional analysis
More - here’s a Literature Lab™ use case.
Literature Lab™ Basic
provides associative analysis mined from 23 million PubMed abstracts. Complex concepts, once impossible to search are now revealed in a few clicks, and relationships among genes, diseases, pathways and other biological functions are clearly identified.
More about Literature Lab™ Basic, the powerful window into the Literature Lab™ database
Gene Retriever:
This application retrieves all genes associated with a List of articles, giving the answer to the age-old question: “I just ran a search on PubMed, what genes are mentioned in the abstracts found by my search?”
The large number of factors involved in the pathogenesis of certain diseases makes identification of a targeted, manageable-sized list of genes involved in these interactions extremely difficult. Gene Retriever helps identify genes that are highly associated with a particular disease, allowing construction of gene panels that contain putative disease signatures. These signatures can be used as biological markers of disease to classify patients for personalized care. An approach has been recently described in which putative novel genes associated with inflammatory bowel disease subtypes were identified using Literature Lab™ Gene Retriever, Literature Lab™ PLUS, and other Literature Lab™ tools: A literature-based approach for curating gene signatures in multifaceted diseases. Journal of Translational Medicine 18, 279 (2020). https://doi.org/10.1186/s12967-020-02408-7
